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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1952 1
1953 1
1954 1
1956 3
1957 2
1958 5
1959 6
1960 4
1961 13
1962 14
1963 14
1964 26
1965 22
1966 20
1967 21
1968 21
1969 30
1970 25
1971 45
1972 38
1973 68
1974 79
1975 104
1976 88
1977 78
1978 62
1979 71
1980 51
1981 43
1982 39
1983 37
1984 41
1985 41
1986 46
1987 42
1988 35
1989 38
1990 50
1991 37
1992 27
1993 50
1994 56
1995 53
1996 42
1997 53
1998 41
1999 43
2000 53
2001 46
2002 51
2003 58
2004 51
2005 60
2006 51
2007 62
2008 56
2009 57
2010 56
2011 63
2012 73
2013 68
2014 70
2015 69
2016 74
2017 61
2018 68
2019 68
2020 89
2021 80
2022 87
2023 104
2024 38

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3,182 results

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Page 1
Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG.
Chen J, Zhou Y, Liu Z, Lu Y, Jiang Y, Cao K, Zhou N, Wang D, Zhang C, Zhou N, Shi K, Zhang L, Zhou L, Wang Z, Zhang H, Tang K, Ma J, Lv J, Huang B. Chen J, et al. Science. 2024 Feb 16;383(6684):eadi3332. doi: 10.1126/science.adi3332. Epub 2024 Feb 16. Science. 2024. PMID: 38359126
In this work, we show that glycogenesis uses its intermediate metabolite uridine diphosphate glucose (UDPG) to antagonize lipogenesis, thus steering both mouse and human hepatocytes toward storing glucose carbon as glycogen. ...Consistent with t …
In this work, we show that glycogenesis uses its intermediate metabolite uridine diphosphate glucose (UDPG) to a …
Biochemical Characterization of Recombinant UDPG-Dependent IAA Glucosyltransferase from Maize (Zea mays).
Ciarkowska A, Ostrowski M, Kozakiewicz A. Ciarkowska A, et al. Int J Mol Sci. 2021 Mar 25;22(7):3355. doi: 10.3390/ijms22073355. Int J Mol Sci. 2021. PMID: 33805949 Free PMC article.
Two sugar-phosphate compounds, ATP and glucose-1-phosphate, have a unique effect on the enzyme by acting as activators at low concentrations and showing inhibitory effect at higher concentrations (above 0.6 and 4 mM for ATP and glucose-1-phosphate, respectively). .. …
Two sugar-phosphate compounds, ATP and glucose-1-phosphate, have a unique effect on the enzyme by acting as activators at low concent …
MK8617 inhibits M1 macrophage polarization and inflammation via the HIF-1alpha/GYS1/UDPG/P2Y(14) pathway.
Qian L, Chen XQ, Kong D, Wang G, Cao Y, Xiao Y, Cao JY, Zou C. Qian L, et al. PeerJ. 2023 Jun 30;11:e15591. doi: 10.7717/peerj.15591. eCollection 2023. PeerJ. 2023. PMID: 37404479 Free PMC article.
Inflammatory indicators in cells were assessed by real-time quantitative reverse-transcription polymerase chain reaction (qRT-PCR), western blot (WB) and immunofluorescence (IF). The level of uridine diphosphate glucose (UDPG) in the cell supernatant w …
Inflammatory indicators in cells were assessed by real-time quantitative reverse-transcription polymerase chain reaction (qRT-PCR), western …
UDP-glucose sensing P2Y(14)R: A novel target for inflammation.
Zhang JZ, Shi NR, Wu JS, Wang X, Illes P, Tang Y. Zhang JZ, et al. Neuropharmacology. 2023 Nov 1;238:109655. doi: 10.1016/j.neuropharm.2023.109655. Epub 2023 Jul 7. Neuropharmacology. 2023. PMID: 37423482 Free article. Review.
Uridine 5'-diphosphoglucose (UDP-G) as a preferential agonist, but also other UDP-sugars, such as UDP galactose, function as extracellular signaling molecules under conditions of cell injury and apoptosis. ...
Uridine 5'-diphosphoglucose (UDP-G) as a preferential agonist, but also other UDP-sugars, such as UDP galactose, function as extracel …
Excessive UDPG resulting from the mutation of UAP1 causes programmed cell death by triggering reactive oxygen species accumulation and caspase-like activity in rice.
Xiao G, Zhou J, Lu X, Huang R, Zhang H. Xiao G, et al. New Phytol. 2018 Jan;217(1):332-343. doi: 10.1111/nph.14818. Epub 2017 Oct 2. New Phytol. 2018. PMID: 28967675 Free article.
Lesion mimic mutants are valuable to unravel the mechanisms governing the programmed cell death (PCD) process. Uridine 5'-diphosphoglucose-glucose (UDPG) functions as a signaling molecule activating multiple pathways in animals, but little is known about its …
Lesion mimic mutants are valuable to unravel the mechanisms governing the programmed cell death (PCD) process. Uridine 5'-diphosphogl …
Enhancement of UDPG synthetic pathway improves ansamitocin production in Actinosynnem pretiosum.
Fan Y, Zhao M, Wei L, Hu F, Imanaka T, Bai L, Hua Q. Fan Y, et al. Appl Microbiol Biotechnol. 2016 Mar;100(6):2651-62. doi: 10.1007/s00253-015-7148-2. Epub 2015 Nov 19. Appl Microbiol Biotechnol. 2016. PMID: 26585444
The biosynthesis of ansamitocins is initialized by the formation of UDP-glucose (UDPG) which is converted from glucose-1-phosphate (G1P). ...The homologous overexpressions of phosphoglucomutase, starch phosphorylase, and UTP-G1P uridylyltransferase, respectiv …
The biosynthesis of ansamitocins is initialized by the formation of UDP-glucose (UDPG) which is converted from glucose- …
Single-molecule investigations of single-chain cellulose biosynthesis.
Hilton MA, Manning HW, Górniak I, Brady SK, Johnson MM, Zimmer J, Lang MJ. Hilton MA, et al. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2122770119. doi: 10.1073/pnas.2122770119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161928 Free PMC article.
We utilize optical tweezers to measure single-strand cellulose biosynthesis by BcsAB from Rhodobacter sphaeroides. Synthesis depends on uridine diphosphate glucose, Mg(2+), and cyclic diguanosine monophosphate, with the last displaying a retention time of 80 …
We utilize optical tweezers to measure single-strand cellulose biosynthesis by BcsAB from Rhodobacter sphaeroides. Synthesis depends on u …
Upregulation of P2Y14 receptor in neutrophils promotes inflammation after myocardial ischemia/reperfusion injury.
Li K, Zhou P, Li J, Cheng Y, Li S, Wang Y, Jiang W, Bai Y, Cao H, Wang D. Li K, et al. Life Sci. 2023 Aug 1;326:121805. doi: 10.1016/j.lfs.2023.121805. Epub 2023 May 24. Life Sci. 2023. PMID: 37236604
Additionally, the expression of P2Y14 receptor was highly induced in neutrophils subjected to uridine 5'-diphosphoglucose (UDP-Glu), which is proven to be secreted by cardiomyocytes during ischemia and reperfusion. ...
Additionally, the expression of P2Y14 receptor was highly induced in neutrophils subjected to uridine 5'-diphosphoglucose (UDP-Glu), …
Nucleotide-sugar metabolism in plants: the legacy of Luis F. Leloir.
Figueroa CM, Lunn JE, Iglesias AA. Figueroa CM, et al. J Exp Bot. 2021 May 18;72(11):4053-4067. doi: 10.1093/jxb/erab109. J Exp Bot. 2021. PMID: 33948638 Review.
He and his co-workers discovered that activated forms of simple sugars, such as UDP-glucose and UDP-galactose, are essential intermediates in the interconversion of sugars. ...
He and his co-workers discovered that activated forms of simple sugars, such as UDP-glucose and UDP-galactose, are essential intermed …
3,182 results